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Question 1

Can you list 10 recombinant proteins which are used in medical practice? Find out where they are used as therapeutics (use the internet).

Answer

Recombinant proteins are obtained from the recombinant DNA technology. This technology involves the transfer of specific genes from an organism into another organism using vectors and restriction enzymes as molecular tools.

Ten recombinant proteins used in medical practice are −

Recombinant protein

Therapeutic use

1.

Insulin

Treatment for type I diabetes mellitus

2.

Interferon-α

Used for chronic hepatitis C

3.

Interferon -β

Used for herpes and viral enteritis

4.

Coagulation factor VII

Treatment of haemophilia A

5.

Coagulation factor IX

Treatment of haemophilia B

6.

DNAase I

Treatment of cystic fibrosis

7.

Anti-thrombin III

Prevention of blood clot

8.

Interferon B.

For treatment of multiple sclerosis

9.

Human recombinant growth hormone

For promoting growth in an individual

10.

Tissue plasminogen activator

Treatment of acute myocardial infection

 

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