Name the first transgenic cow. Which gene was introduced in this cow?
Animals that have been permanently engineered by the gene insertion are known as transgenic animals and the foreign genes are added are known as transgenes. In 1981, Ralph Brinster and Richard Palmiter introduced first transgenic animal, by introducing a gene for rat growth hormone (GH) into fertilized eggs of mice.
First transgenic cow name was Rosie and is considered as different from normal cow. Transgenic cow that contains cDNA which codes for the antibacterial human iron- binding protein called lactoferrin have been produced. In this cow, human genes are transferred that are expressed in mammary tissues and then the milk contains nutritionally more balanced product, α- lactalbumin for human bodies than natural cow milk.
Consult internet and find out how to make orally active protein pharmaceutical. What is the major problem to be encountered?
Fill in the blanks:
(a) Humans reproduce __________. (asexually/sexually)
(b) Humans are__________. (oviparous/viviparous/ovoviviparous)
(c) Fertilization is __________ in humans. (external/internal)
(d) Male and female gametes are __________. (diploid/haploid)
(e) Zygote is __________. (diploid/haploid)
(f) The process of release of the ovum from a mature follicle is called__________.
(g) Ovulation is induced by a hormone called the __________.
(h) The fusion of male and female gametes is called _____________.
(i) Fertilisation takes place in _____________.
(j) Zygote divides to form _____________which is implanted in uterus.
(k) The structure which provides vascular connection between fetus and uterus is called ____________.